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Stephen Henry

COVID‐19 antibody screening with SARS‐CoV‐2 red cell kodecytes using routine serologic diagnostic platforms

Transfusion Journal Open Access – https://doi.org/10.1111/trf.16327 Nagappan, R, Flegel, WA, Srivastava, K, et al. COVID‐19 antibody screening with SARS‐CoV‐2 red cell kodecytes using routine serologic diagnostic platforms. Transfusion. 2021; 61: 1171– 1180 Abstract Background The Coronavirus disease 2019 (COVID‐19) pandemic is having a major global impact, and the resultant response… Read More »COVID‐19 antibody screening with SARS‐CoV‐2 red cell kodecytes using routine serologic diagnostic platforms

Incidence in plasma of low level antibodies against three xenotransplantation and immunotherapeutic glycan antigens

AIMS Allergy and Immunology – DOI: 10.3934/Allergy.2020007 Holly E Perry, Ivan Ryzhov, Oxana Galanina, Nicolai V Bovin, Stephen M Henry. Incidence in plasma of low level antibodies against three xenotransplantation and immunotherapeutic glycan antigens[J]. AIMS Allergy and Immunology, 2020, 4(4): 75-87 Abstract Antibodies against xeno-glycan antigens terminating with the saccharides… Read More »Incidence in plasma of low level antibodies against three xenotransplantation and immunotherapeutic glycan antigens

Differential recognition of lipid domains by two Gb3-binding lectins

Nature Scientific Reports Open Access – https://doi.org/10.1038/s41598-020-66522-8 Schubert, T., Sych, T., Madl, J. et al. Differential recognition of lipid domains by two Gb3-binding lectins. Sci Rep 10, 9752 (2020) Abstract The two lectins LecA from Pseudomonas aeruginosa and the B-subunit of Shiga toxin from Shigella dysenteriae (StxB) share the glycosphingolipid… Read More »Differential recognition of lipid domains by two Gb3-binding lectins

Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE

Chemistry Open – https://doi.org/10.1002/open.201900276 Zalygin, A., Solovyeva, D., Vaskan, I., Henry, S., Schaefer, M., Volynsky, P., Tuzikov, A., Korchagina, E., Ryzhov, I., Nizovtsev, A., Mochalov, K., Efremov, R., Shtykova, E., Oleinikov, V. and Bovin, N. Abstract The synthetic function‐spacer‐lipid (FSL) amphiphile biotin‐CMG‐DOPE is widely used for delicate ligation of living… Read More »Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE

Kodecytes: modifying the surface of red blood cells

ISBT Science Series Open Access – https://doi.org/10.1111/voxs.12545 Henry, S. (2020), Kodecytes: modifying the surface of red blood cells. VOXS, 15: 303-309. Abstract There are few routine techniques available to modify the antigenic surface of red blood cells (RBC). Primarily, modification techniques involve antigen destruction with enzymes or denaturing chemicals. In… Read More »Kodecytes: modifying the surface of red blood cells

Synthesis of blood group Forssman pentasaccharide GalNAcα1-3GalNAcβ1-3Galα1-4Galβ1-4Glcβ–R

Mendeleev Communication – https://doi.org/10.1016/j.mencom.2019.09.034 Summary: Synthesis of Forssman glycolipid FSL-FS-5. Kodeyctes and native FORS1+ donor used to compare reactivity toward monoclonal anti-Forssman antibody Inna S. Popova,Elena Yu. Korchagina, Marina A. Sablina, Alexander S. Paramonov, Annika K. Hult, Stephen M. Henry and Nicolai V. Bovin, Mendeleev Commun., (2019) 29, 578-580 Synthesis… Read More »Synthesis of blood group Forssman pentasaccharide GalNAcα1-3GalNAcβ1-3Galα1-4Galβ1-4Glcβ–R

A standardized kodecyte method to quantify ABO antibodies in undiluted plasma of patients before ABO‐incompatible kidney transplantation

Transfusion Journal Open Access – https://doi.org/10.1111/trf.15247 Summary: Kodecytes can quantitate ABO antibodies in plasma without the requirement to dilute sample Holly Perry, Nicolai Bovin & Stephen Henry, Transfusion (2019) 59;2131-2140 Abstract BACKGROUND The ABO transplantation barrier can be breached if antibody is reduced to low levels. Current serologic methods involve… Read More »A standardized kodecyte method to quantify ABO antibodies in undiluted plasma of patients before ABO‐incompatible kidney transplantation

Kode Technology – a universal cell surface glycan modification technology

Journal of the Royal Society of New Zealand Open Access – https://doi.org/10.1080/03036758.2018.1546195 Stephen M. Henry & Nicolai V. Bovin, Journal of the Royal Society of New Zealand (2018), 49:2, 100-113 ABSTRACT Cells are highly decorated with glycans (carbohydrates) and this complex and dominating coating on cells, which also carries the… Read More »Kode Technology – a universal cell surface glycan modification technology

Rapid one-step biotinylation of biological and non-biological surfaces

Nature Scientific Reports Open Access – https://doi.org/10.1038/s41598-018-21186-3 Summary: We describe a rapid one-step method to biotinylate virtually any biological or non-biological surface. Contacting a solution of biotin-spacer-lipid constructs with a surface will form a coating within seconds on non-biological surfaces or within minutes on most biological membranes including membrane viruses.… Read More »Rapid one-step biotinylation of biological and non-biological surfaces

Applications for kodecytes in immunohaematology

ISBT Science Series Open Access – https://doi.org/10.1111/voxs.12403 Henry S, Perry H, Bovin N. Applications for kodecytes in immunohematology. ISBT Science Series 2017;0:1-9 Abstract Red cells used in immunohaematology are mostly limited to those that nature provides. Very few techniques are available for adding new functionalities to cells, without affecting their… Read More »Applications for kodecytes in immunohaematology